Información del producto
IGF-IR (phospho Tyr1161) rabbit pAb
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
Synthesized phospho-peptide around the phosphorylation site of human IGF-IR (phospho Tyr1161)
Subcellular Location
Cell membrane
Single-pass type I membrane protein .
Single-pass type I membrane protein .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
3480
Observed Band
pro: 155kD, recetor beta: 95kD
Other Name
CD antigen CD220
CD antigen CD221
IGF-I receptor
IGF1R
INSR
IR
Insulin-like growth factor 1 receptor
Insulin-like growth factor I receptor
Insulin receptor
CD antigen CD221
IGF-I receptor
IGF1R
INSR
IR
Insulin-like growth factor 1 receptor
Insulin-like growth factor I receptor
Insulin receptor
Background
This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It