Información del producto
PKC δ (phospho Ser645) rabbit pAb
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human PKC delta around the phosphorylation site of Ser645. AA range:612-661
Subcellular Location
Cytoplasm . Cytoplasm, perinuclear region . Nucleus . Cell membrane
Peripheral membrane protein . Mitochondrion . Endomembrane system . Translocates to the mitochondria upon apoptotic stimulation. Upon activation, translocates to the plasma membrane followed by partial location to the endolysosomes (PubMed:17303575). .
Peripheral membrane protein . Mitochondrion . Endomembrane system . Translocates to the mitochondria upon apoptotic stimulation. Upon activation, translocates to the plasma membrane followed by partial location to the endolysosomes (PubMed:17303575). .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Monkey
Monkey
Human Gen
5580
Observed Band
77kD
Other Name
PRKCD
Protein kinase C delta type
Tyrosine-protein kinase PRKCD
nPKC-delta
Protein kinase C delta type
Tyrosine-protein kinase PRKCD
nPKC-delta
Background
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved