Información del producto
JNK1/2/3 (phospho Tyr185) rabbit pAb
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
IF: 1:50-200 Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human SAPK/JNK around the phosphorylation site of Tyr185. AA range:151-200
Subcellular Location
Cytoplasm . Nucleus . Cell junction, synapse . In the cortical neurons, predominantly cytoplasmic and associated with the Golgi apparatus and endosomal fraction. Increased neuronal activity increases phosphorylated form at synapses (By similarity). Coloca
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
5599/5601/5602
Observed Band
45kD
Other Name
JNK-46
JNK1
JNK2
MAPK 8
MAPK8
MAPK9
MAP kinase 8
Mi
Mitogen-activated protein kinase 8
PRKM8
PRKM9
SAPK1
SAPK1A
SAPK1C
SAPK1c
Stress-activated protein kinase 1c
Stress-activated protein kinase JNK1
c-Jun N-terminal kinase 1
JNK1
JNK2
MAPK 8
MAPK8
MAPK9
MAP kinase 8
Mi
Mitogen-activated protein kinase 8
PRKM8
PRKM9
SAPK1
SAPK1A
SAPK1C
SAPK1c
Stress-activated protein kinase 1c
Stress-activated protein kinase JNK1
c-Jun N-terminal kinase 1
Background
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription