Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human MKP-1/2 around the phosphorylation site of Ser296/318. AA range:261-310
Subcellular Location
Nucleus .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
1843/1846
Observed Band
45kD
Other Name
CL100
DUSP1
DUSP4
Dual specificity protein phosphatase 1
Dual specificity protein phosphatase hVH1
MAP kinase phosphatase 1
MKP-1
MKP1
Mitogen-activated protein kinase phosphatase 1
PTPN10
Protein-tyrosine phosphatase CL100
VH1
Background
The expression of DUSP1 gene is induced in human skin fibroblasts by oxidative/heat stress and growth factors. It specifies a protein with structural features similar to members of the non-receptor-type protein-tyrosine phosphatase family, and which has