Información del producto
FRS2 (phospho Tyr436) rabbit pAb
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human FRS2 around the phosphorylation site of Tyr436. AA range:402-451
Subcellular Location
Endomembrane system. Cytoplasmic, membrane-bound.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Monkey
Mouse
Monkey
Mouse
Human Gen
10818
Observed Band
65kD
Other Name
FGFR-signaling adaptor SNT
FGFR substrate 2
FRS2
Fibroblast growth factor receptor substrate 2
SNT-1
Suc1-associated neurotrophic factor target 1
FGFR substrate 2
FRS2
Fibroblast growth factor receptor substrate 2
SNT-1
Suc1-associated neurotrophic factor target 1
Background
function:Adapter protein that links FGR and NGF receptors to downstream signaling pathways. Involved in the activation of MAP kinases. Modulates signaling via SHC1 by competing for a common binding site on NTRK1.,PTM:Phosphorylated on tyrosine residues up