Información del producto
Caspase-9 (phospho Thr125) rabbit pAb
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human Caspase 9 around the phosphorylation site of Thr125. AA range:91-140
Subcellular Location
nucleus,mitochondrion,cytosol,apoptosome,
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
842
Observed Band
46kD
Other Name
APAF-3
Apoptotic protease-activating factor 3
Apoptotic protease Mch-6
CASP-9
CASP9
Caspase-9
ICE-LAP6
ICE-like apoptotic protease 6
MCH6
Apoptotic protease-activating factor 3
Apoptotic protease Mch-6
CASP-9
CASP9
Caspase-9
ICE-LAP6
ICE-like apoptotic protease 6
MCH6
Background
CASP9 encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at
this step is thought to be one of the earliest in the caspase activation cascade. Caspase 9 is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants.
this step is thought to be one of the earliest in the caspase activation cascade. Caspase 9 is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants.