Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
Synthesized phospho-peptide around the phosphorylation site of human NFκB-p105/p50 (phospho Ser337)
Subcellular Location
Nucleus. Cytoplasm. Nuclear, but also found in the cytoplasm in an inactive form complexed to an inhibitor (I-kappa-B).
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Human Gen
4790
Observed Band
105+50kD
Other Name
DNA-binding factor KBF1
EBP-1
NFKB1
Nuclear factor NF-kappa-B p105 subunit
Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
Background
nuclear factor kappa B subunit 1(NFKB1) Homo sapiens This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor