Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human Synaptotagmin around the phosphorylation site of Ser309. AA range:276-325
Subcellular Location
Cytoplasmic vesicle, secretory vesicle membrane
Single-pass membrane protein . Cytoplasm .
Single-pass membrane protein . Cytoplasmic vesicle, secretory vesicle, chromaffin granule membrane
Single-pass membrane protein . Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
6857/127833
Observed Band
47kD
Other Name
SVP65
SYT
SYT1
SYT2
Synaptotagmin-1
Synaptotagmin-2
Synaptotagmin I
Synaptotagmin II
SytI
SytII
p65
Background
The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin-1 participates in triggering neurotransmitter release at the