Storage Conditions
-20°C/1 year
Applications
ELISA
IF
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human FGFR1 around the phosphorylation site of Tyr154. AA range:121-170
Subcellular Location
Cell membrane
Single-pass type I membrane protein. Nucleus. Cytoplasm, cytosol. Cytoplasmic vesicle. After ligand binding, both receptor and ligand are rapidly internalized. Can translocate to the nucleus after internalization, or by translocation from the endoplasmic
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
2260
Observed Band
145 91kD
Other Name
BFGFR
BFGFR
Basic fibroblast growth factor receptor 1
CD antigen CD331
CEK
FGFBR
FGFR-1
FGFR1
FLG
FLT-2
FLT2
Fibroblast growth factor receptor 1
Fms-like tyrosine kinase 2
HBGFR
N-sam
Proto-oncogene c-Fgr
bFGF-R-1
Background
The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affini