mTOR (phospho Thr2446) rabbit pAb
  • mTOR (phospho Thr2446) rabbit pAb
ELK

mTOR (phospho Thr2446) rabbit pAb

Ref: ELK-ES1436-50ul
50ul

Información del producto

mTOR (phospho Thr2446) rabbit pAb

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Información adicional
Storage Conditions -20°C/1 year
Applications ELISA
IHC
WB
Concentration 1 mg/ml
Recomended Dilution ELISA 2000-20000
IHC-p 1:50-300
WB 1:500-2000
Type Clonality Polyclonal
Immunogen The antiserum was produced against synthesized peptide derived from human mTOR around the phosphorylation site of Thr2446. AA range:2412-2461
Subcellular Location Cytoplasmic side . Golgi apparatus membrane
Cytoplasmic side . Lysosome . Cytoplasm . Nucleus, PML body . Microsome membrane . Lysosome membrane . Cytoplasmic vesicle, phagosome . Shuttles between cytoplasm and nucleus. Accumulates in the nucleus in response to hypoxia (By similarity). Targeting to
Cytoplasmic side . Mitochondrion outer membrane
Endoplasmic reticulum membrane
Peripheral membrane protein
Peripheral membrane protein
Peripheral membrane protein
Iso type IgG
Tissue Source Rabbit
Reactivity Human
Mouse
Rat
Human Gen 2475
Observed Band 220kD
Other Name FK506-binding protein 12-rapamycin complex-associated protein 1
FKBP12-rapamycin complex-associated protein
FRAP
FRAP1
FRAP2
MTOR
Mammalian target of rapamycin
Mechanistic tar
RAFT1
RAPT1
Serine/threonine-protein kinase mTOR
mTOR
Background The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arres