Información del producto
SHIP-1 (phospho Tyr1021) rabbit pAb
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
ELISA 1:2000-20000
IF/ICC 1:50-200
IHC-p 1:50-200
WB 1:500-2000
IF/ICC 1:50-200
IHC-p 1:50-200
WB 1:500-2000
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human SHIP1 around the phosphorylation site of Tyr1021. AA range:987-1036
Subcellular Location
Cytoplasm . Cell membrane
Peripheral membrane protein . Membrane raft . Cytoplasm, cytoskeleton . Membrane
Peripheral membrane protein . Translocates to the plasma membrane when activated, translocation is probably due to different mechanisms depending on the stimulus and cell type. Translocates from the cytoplasm to membrane ruffles in a FCGR3/CD16-dependent
Peripheral membrane protein . Membrane raft . Cytoplasm, cytoskeleton . Membrane
Peripheral membrane protein . Translocates to the plasma membrane when activated, translocation is probably due to different mechanisms depending on the stimulus and cell type. Translocates from the cytoplasm to membrane ruffles in a FCGR3/CD16-dependent
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
3635
Observed Band
133kD
Other Name
4,5-trisphosphate 5-phosphatase 1
INPP5D
Inositol polyphosphate-5-phosphatase of 145 kDa
Phosphatidylinositol 3
SH2 domain-containing inositol 5'-phosphatase 1
SH2 domain-containing inositol phosphatase 1
SHIP
SHIP-1
SHIP1
SIP-145
INPP5D
Inositol polyphosphate-5-phosphatase of 145 kDa
Phosphatidylinositol 3
SH2 domain-containing inositol 5'-phosphatase 1
SH2 domain-containing inositol phosphatase 1
SHIP
SHIP-1
SHIP1
SIP-145
Background
This gene is a member of the inositol polyphosphate-5-phosphatase (INPP5) family and encodes a protein with an N-terminal SH2 domain, an inositol phosphatase domain, and two C-terminal protein interaction domains. Expression of this protein is restricted