Información del producto
Shb (phospho Tyr246) rabbit pAb
Información adicional
Storage Conditions
-20°C/1 year
Applications
IHC
WB
WB
Concentration
1 mg/ml
Recomended Dilution
IHC-p 1:50-300
WB 1:500-2000
WB 1:500-2000
Type Clonality
Polyclonal
Immunogen
Synthesized phospho-peptide around the phosphorylation site of human Shb (phospho Tyr246)
Subcellular Location
Cytoplasm. Cell membrane
Cytoplasmic side. Associates with membrane lipid rafts upon TCR stimulation.
Peripheral membrane protein
Cytoplasmic side. Associates with membrane lipid rafts upon TCR stimulation.
Peripheral membrane protein
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Mouse
Human Gen
6461
Observed Band
55kD
Other Name
SH2 domain-containing adapter protein B
SHB
SHB
Background
domain:The SH2 domain preferentially binds phosphopeptides with the consensus sequence Y-[TVI]-X-L and mediates interaction with PDGFRA, PDGFRB, FGRFR1, IL2RB, IL2RG, CD3Z and CRK/CrKII.,function:Adapter protein which regulates several signal transduction