Información del producto
p70 S6 kinase α (phospho Ser447) rabbit pAb
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human p70 S6 Kinase around the phosphorylation site of Ser424. AA range:414-463
Subcellular Location
Cell junction, synapse, synaptosome . Mitochondrion outer membrane. Mitochondrion. Colocalizes with URI1 at mitochondrion.
[Isoform Alpha II]: Cytoplasm.
[Isoform Alpha I]: Nucleus. Cytoplasm.
[Isoform Alpha II]: Cytoplasm.
[Isoform Alpha I]: Nucleus. Cytoplasm.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
6198
Observed Band
60kD
Other Name
70 kDa ribosomal protein S6 kinase 1
P70S6K1
RPS6KB1
Ribosomal protein S6 kinase I
Ribosomal protein S6 kinase beta-1
S6K-beta-1
S6K1
STK14A
Serine/threonine-protein kinase 14A
p70 S6 kinas
p70 ribosomal S6 kinase alpha
p70-S6K 1
P70S6K1
RPS6KB1
Ribosomal protein S6 kinase I
Ribosomal protein S6 kinase beta-1
S6K-beta-1
S6K1
STK14A
Serine/threonine-protein kinase 14A
p70 S6 kinas
p70 ribosomal S6 kinase alpha
p70-S6K 1
Background
ribosomal protein S6 kinase B1(RPS6KB1) Homo sapiens This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis,