ELK

p53 (phospho Thr18) rabbit pAb

Name: p53 (phospho Thr18) rabbit pAb
Brand: ELK
SKU: ELK-ES1388-50ul

Ref: ELK-ES1388-50ul

50ul

Información del producto

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Información adicional

Storage Conditions -20°C/1 year

Applications ELISA
IF
IHC
WB

Concentration 1 mg/ml

Recomended Dilution IF: 1:50-200 WB 1:500-2000, IHC 1:50-300 IHC 1:50-300

Type Clonality Polyclonal

Immunogen The antiserum was produced against synthesized peptide derived from human p53 around the phosphorylation site of Thr18. AA range:1-50

Subcellular Location Cytoplasm . Nucleus . Nucleus, PML body . Endoplasmic reticulum . Mitochondrion matrix . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Recruited into PML bodies together with CHEK2 (PubMed:12810724). Translocates to mitochondria upo
[Isoform 1]: Nucleus . Cytoplasm. Predominantly nuclear but localizes to the cytoplasm when expressed with isoform 4.
[Isoform 2]: Nucleus. Cytoplasm. Localized mainly in the nucleus with minor staining in the cytoplasm.
[Isoform 3]: Nucleus. Cytoplasm. Localized in the nucleus in most cells but found in the cytoplasm in some cells.
[Isoform 4]: Nucleus. Cytoplasm. Predominantly nuclear but translocates to the cy

Iso type IgG

Tissue Source Rabbit

Reactivity Human
Mouse
Rat

Human Gen 7157

Observed Band 46kD

Other Name Antigen NY-CO-13
Cellular tumor antigen p53
P53
Phosphoprotein p53
TP53
Tumor suppressor p53

Background tumor protein p53(TP53) Homo sapiens This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of targe