Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human MKK3 around the phosphorylation site of Ser189. AA range:173-222
Subcellular Location
nucleoplasm,cytoplasm,cytosol,membrane,
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
5606
Observed Band
39kD
Other Name
Dual specificity mitogen-activated protein kinase kinase 3
MAP2K3
MAPK/ERK kinase 3
MAPKK 3
MAP kinase kinase 3
MEK3
MEK 3
MKK3
PRKMK3
SAPKK-2
SAPKK2
SAPK kinase 2
SKK2
Stress-activated protein kinase kinase 2
Background
The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is activated by mitogenic and environmental stress, and participates in the MAP kinase-mediated signaling cascade. It phosphory