Información del producto
MEK-2 (phospho Thr394) rabbit pAb
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
IP
WB
IF
IHC
IP
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunoprecipitation: 2-5 ug/mg lysate. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human MEK2 around the phosphorylation site of Thr394. AA range:261-310
Subcellular Location
Cytoplasm . Membrane
Peripheral membrane protein . Membrane localization is probably regulated by its interaction with KSR1. .
Peripheral membrane protein . Membrane localization is probably regulated by its interaction with KSR1. .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
5606
Other Name
Dual specificity mitogen-activated protein kinase kinase 2
ERK activator kinase 2
MAP2K2
MAPK/ERK kinase 2
MAPKK 2
MAP kinase kinase 2
MEK 2
MEK2
MKK2
PRKMK2
ERK activator kinase 2
MAP2K2
MAPK/ERK kinase 2
MAPKK 2
MAP kinase kinase 2
MEK 2
MEK2
MKK2
PRKMK2
Background
The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2