Información del producto
IGF-IR (phospho Tyr1165/Y1166) rabbit pAb
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
WB
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human IGF1R around the phosphorylation site of Tyr1165/Tyr1166. AA range:1131-1180
Subcellular Location
Cell membrane
Single-pass type I membrane protein .
Single-pass type I membrane protein .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Monkey
Mouse
Rat
Monkey
Mouse
Rat
Human Gen
3480
Observed Band
pro: 155kD, recetor beta: 95kD
Other Name
CD antigen CD221
IGF-I receptor
IGF1R
Insulin-like growth factor 1 receptor
Insulin-like growth factor I receptor
IGF-I receptor
IGF1R
Insulin-like growth factor 1 receptor
Insulin-like growth factor I receptor
Background
This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It