Información del producto
HSP27 (phospho Ser15) rabbit pAb
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human HSP27 around the phosphorylation site of Ser15. AA range:5-54
Subcellular Location
Cytoplasm . Nucleus . Cytoplasm, cytoskeleton, spindle . Cytoplasmic in interphase cells. Colocalizes with mitotic spindles in mitotic cells. Translocates to the nucleus during heat shock and resides in sub-nuclear structures known as SC35 speckles or nuc
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Monkey
Monkey
Human Gen
3315
Observed Band
26kD
Other Name
28 kDa heat shock protein
Estrogen-regulated 24 kDa protein
HSP 27
HSP27
HSP28
HSPB1
Heat shock 27 kDa protein
Heat shock protein beta-1
HspB1
SRP27
Stress-responsive protein 27
Estrogen-regulated 24 kDa protein
HSP 27
HSP27
HSP28
HSPB1
Heat shock 27 kDa protein
Heat shock protein beta-1
HspB1
SRP27
Stress-responsive protein 27
Background
The protein encoded by this gene is induced by environmental stress and developmental changes. The encoded protein is involved in stress resistance and actin organization and translocates from the cytoplasm to the nucleus upon stress induction. Defects in