Información del producto
Hrs (phospho Tyr216) rabbit pAb
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
WB
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
Synthesized phospho-peptide around the phosphorylation site of human Hrs (phospho Tyr216)
Subcellular Location
Cytoplasm . Early endosome membrane
Cytoplasmic side . Endosome, multivesicular body membrane
Peripheral membrane protein
Peripheral membrane protein . Colocalizes with UBQLN1 in ubiquitin-rich cytoplasmic aggregates that are not endocytic compartments. .
Cytoplasmic side . Endosome, multivesicular body membrane
Peripheral membrane protein
Peripheral membrane protein . Colocalizes with UBQLN1 in ubiquitin-rich cytoplasmic aggregates that are not endocytic compartments. .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
9146
Observed Band
115kD
Other Name
HGS
HRS
Hepatocyte growth factor-regulated tyrosine kinase substrate
Hrs
Protein pp110
HRS
Hepatocyte growth factor-regulated tyrosine kinase substrate
Hrs
Protein pp110
Background
The protein encoded by this gene regulates endosomal sorting and plays a critical role in the recycling and degradation of membrane receptors. The encoded protein sorts monoubiquitinated membrane proteins into the multivesicular body, targeting these prot