Storage Conditions
-20°C/1 year
Applications
ELISA
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
Synthesized phospho-peptide around the phosphorylation site of human Erbin (phospho Tyr1104)
Subcellular Location
Cell junction, hemidesmosome . Nucleus membrane . Basolateral cell membrane . Found in hemidesmosomes, which are cell-substrate adhesion complexes in stratified epithelia. In transfected cells, either diffusely distributed over the cytoplasm or concentrat
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
55914
Observed Band
172kD
Other Name
Densin-180-like protein
ERBB2IP
ERBIN
Erbb2-interacting protein
Erbin
KIAA1225
LAP2
Protein LAP2
Background
This gene is a member of the leucine-rich repeat and PDZ domain (LAP) family. The encoded protein contains 17 leucine-rich repeats and one PDZ domain. It binds to the unphosphorylated form of the ERBB2 protein and regulates ERBB2 function and localization