Storage Conditions
-20°C/1 year
Applications
ELISA
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
Synthesized phospho-peptide around the phosphorylation site of human EphA2 (phospho Tyr588)
Subcellular Location
Cell membrane
Single-pass type I membrane protein . Cell junction, focal adhesion . Present at regions of cell-cell contacts but also at the leading edge of migrating cells (PubMed:19573808, PubMed:20861311). Relocates from the plasma membrane to the cytoplasmic and pe
Single-pass type I membrane protein . Cell projection, lamellipodium membrane
Single-pass type I membrane protein . Cell projection, ruffle membrane
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Human Gen
1969
Observed Band
130kD
Other Name
ECK
EPHA2
Ephrin type-A receptor 2
Epithelial cell kinase
Tyrosine-protein kinase receptor ECK
Background
This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically ha