Información del producto
eIF2α (phospho Ser51) rabbit pAb
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
IF: 1:50-200 Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human eIF2 alpha around the phosphorylation site of Ser51. AA range:21-70
Subcellular Location
Cytoplasm, Stress granule . Colocalizes with NANOS3 in the stress granules. .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Dog
Fish
Human
Mouse
Pig
Rat
Fish
Human
Mouse
Pig
Rat
Human Gen
1965
Observed Band
38kD
Other Name
EIF2A
EIF2S1
Eukaryotic translation initiation factor 2 subunit 1
Eukaryotic translation initiation factor 2 subunit alpha
eIF-2-alpha
eIF-2A
eIF-2alpha
EIF2S1
Eukaryotic translation initiation factor 2 subunit 1
Eukaryotic translation initiation factor 2 subunit alpha
eIF-2-alpha
eIF-2A
eIF-2alpha
Background
MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987 [PubMed 2948954]).[supplied by OMIM, Feb 2010],
MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3
The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is
MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3
The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is