ELK

EGFR (phospho Tyr1197) rabbit pAb

Name: EGFR (phospho Tyr1197) rabbit pAb
Brand: ELK
SKU: ELK-ES1303-50ul

Ref: ELK-ES1303-50ul

50ul

Información del producto

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Información adicional

Storage Conditions -20°C/1 year

Applications ELISA
IF
IHC
WB

Concentration 1 mg/ml

Recomended Dilution Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

Type Clonality Polyclonal

Immunogen The antiserum was produced against synthesized peptide derived from human EGFR around the phosphorylation site of Tyr1197. AA range:1161-1210

Subcellular Location Cell membrane
Single-pass type I membrane protein . Endoplasmic reticulum membrane
Single-pass type I membrane protein. Endosome . Endosome membrane. Nucleus . In response to EGF, translocated from the cell membrane to the nucleus via Golgi and ER (PubMed:20674546, PubMed:17909029). Endocytosed upon activation by ligand (PubMed:2790960,
Single-pass type I membrane protein. Golgi apparatus membrane
Single-pass type I membrane protein. Nucleus membrane
[Isoform 2]: Secreted.

Iso type IgG

Tissue Source Rabbit

Reactivity Human
Mouse
Rat

Human Gen 1956

Observed Band 175kD

Other Name EGFR
ERBB
ERBB1
Epidermal growth factor receptor
HER1
Proto-oncogene c-ErbB-1
Receptor tyrosine-protein kinase erbB-1

Background The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growt