Información del producto
EGFR (phospho Tyr1110) rabbit pAb
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
WB
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human EGFR around the phosphorylation site of Tyr1110. AA range:1077-1126
Subcellular Location
Cell membrane
Single-pass type I membrane protein . Endoplasmic reticulum membrane
Single-pass type I membrane protein. Endosome . Endosome membrane. Nucleus . In response to EGF, translocated from the cell membrane to the nucleus via Golgi and ER (PubMed:20674546, PubMed:17909029). Endocytosed upon activation by ligand (PubMed:2790960,
Single-pass type I membrane protein. Golgi apparatus membrane
Single-pass type I membrane protein. Nucleus membrane
[Isoform 2]: Secreted.
Single-pass type I membrane protein . Endoplasmic reticulum membrane
Single-pass type I membrane protein. Endosome . Endosome membrane. Nucleus . In response to EGF, translocated from the cell membrane to the nucleus via Golgi and ER (PubMed:20674546, PubMed:17909029). Endocytosed upon activation by ligand (PubMed:2790960,
Single-pass type I membrane protein. Golgi apparatus membrane
Single-pass type I membrane protein. Nucleus membrane
[Isoform 2]: Secreted.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
1956
Observed Band
175kD
Other Name
EGFR
ERBB
ERBB1
Epidermal growth factor receptor
HER1
Proto-oncogene c-ErbB-1
Receptor tyrosine-protein kinase erbB-1
ERBB
ERBB1
Epidermal growth factor receptor
HER1
Proto-oncogene c-ErbB-1
Receptor tyrosine-protein kinase erbB-1
Background
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growt