Información del producto
ATF-2 (phospho Ser62) rabbit pAb
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
IP
WB
IF
IHC
IP
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunoprecipitation: 2-5 ug/mg lysate. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human ATF2 around the phosphorylation site of Ser62 or 44. AA range:29-78
Subcellular Location
Nucleus. Cytoplasm. Mitochondrion outer membrane. Shuttles between the cytoplasm and the nucleus and heterodimerization with JUN is essential for the nuclear localization. Localization to the cytoplasm is observed under conditions of cellular stress and i
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
1386
Other Name
ATF2
Activating transcription factor 2
CREB-2
CREB2
CREBP1
Cyclic AMP-dependent transcription factor ATF-2
Cyclic AMP-responsive element-binding protein 2
cAMP-dependent transcription factor ATF-2
cAMP-responsive element-binding pro
Activating transcription factor 2
CREB-2
CREB2
CREBP1
Cyclic AMP-dependent transcription factor ATF-2
Cyclic AMP-responsive element-binding protein 2
cAMP-dependent transcription factor ATF-2
cAMP-responsive element-binding pro
Background
activating transcription factor 2(ATF2) Homo sapiens This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. The encoded protein has been identified as a moonlighting protein based on its ability
thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. The encoded protein may also be involved in cell's DNA damage response independent of its role in transcriptional regulation.
thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. The encoded protein may also be involved in cell's DNA damage response independent of its role in transcriptional regulation.