Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
Synthesized acetyl-peptide derived from the human Ku-70 around the acetylation site of K542.
Subcellular Location
Nucleus . Chromosome .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
2547
Observed Band
100,70kD
Other Name
5'-dRP lyase Ku70
5'-deoxyribose-5-phosphate lyase Ku70
70 kDa subunit of Ku antigen
ATP-dependent DNA helicase 2 subunit 1
ATP-dependent DNA helicase II 70 kDa subunit
CTC75
CTCBF
CTC box-binding factor 75 kDa subunit
DNA repair protein XRCC6
G22P1
Ku70
Lupus Ku autoantigen protein p70
TLAA
Thyroid-lupus autoantigen
X-ray repair complementing defective repair in Chinese hamster cells 6
X-ray repair cross-complementing protein 6
XRCC6
Background
The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of non