Información del producto
Cleaved-MMP-14 (Y112) rabbit pAb
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
WB
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human MMP14. AA range:93-142
Subcellular Location
Membrane
Single-pass type I membrane protein . Melanosome. Cytoplasm. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Forms a complex with BST2 and localizes to the cytoplasm.
Single-pass type I membrane protein . Melanosome. Cytoplasm. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Forms a complex with BST2 and localizes to the cytoplasm.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
4323
Observed Band
53kD
Other Name
MMP-14
MMP-X1
MMP14
MT-MMP 1
MT1-MMP
MT1MMP
MTMMP1
Matrix metalloproteinase-14
Membrane-type-1 matrix metalloproteinase
Membrane-type matrix metalloproteinase 1
MMP-X1
MMP14
MT-MMP 1
MT1-MMP
MT1MMP
MTMMP1
Matrix metalloproteinase-14
Membrane-type-1 matrix metalloproteinase
Membrane-type matrix metalloproteinase 1
Background
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as art
each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion. [provi
each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion. [provi