Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Applications
IHC
Concentration
1mg/mL
Recomended Dilution
IHC 1:100-200
Type Clonality
Monoclonal
Immunogen
Synthetic Peptide
Subcellular Location
Cytoplasm, Nucleus
Iso type
IgG1
Tissue Source
Mouse
Reactivity
Human, Mouse, Rat
Human Gen
5970
Observed Band
65kDa
Other Name
NF kappa B p65, NFKB3, p65, p65 NF kB, RELA, TF65, Transcription Factor p65
Background
NFkB p65 is ubiquitinated leading to its proteosomal degradation, which is required for termination of the NFkB response. Phosphorylation of NFkB p65 on S536 stimulates acetylation of K310 by CBP, enhancing transcriptional activity. NFkB p65 is also acety