Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Applications
IHC
Concentration
1mg/mL
Recomended Dilution
IHC 1:100-200
Type Clonality
Monoclonal
Immunogen
Recombinant Protein
Subcellular Location
Cytoplasmic vesicle, Nucleus
Iso type
IgG1
Tissue Source
Mouse
Reactivity
Human, Rat, Mouse
Human Gen
472
Observed Band
350kDa
Other Name
AT1,ATA,ATDC,TEL1,A-T mutated antibody
Background
Ataxia telangiectasia mutated kinase (ATM) is a serine/threonine kinase that regulates cell cycle checkpoints and DNA repair. ATM kinase regulates a number of proteins involved in cell cycle checkpoint control, apoptosis, and DNA repair.