Información del producto
Beclin-1 (5C2) Mouse mAb
Información adicional
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Applications
WB, IHC
Concentration
1mg/mL
Recomended Dilution
WB 1:1,000-2,000 IHC 1:100-200
Type Clonality
Monoclonal
Immunogen
Synthetic Peptide
Subcellular Location
Cytoplasm, Cytoplasmic vesicle, Endoplasmic reticulum, Endosome, Golgi apparatus, Membrane, Mitochondrion, Nucleus
Iso type
IgG1
Tissue Source
Mouse
Reactivity
Human, Rat, Mouse
Human Gen
8678
Observed Band
60kDa
Other Name
ATG6, Bcl-2 interacting protein beclin, BECN1, Coiled coil myosin like BCL2 interacting protein
Background
Autophagy is a catabolic process for the autophagosomic-lysosomal degradation of proteins activated in response to nutrient deprivation and in neurodegenerative conditions. One of the proteins critical to this process is Beclin-1.