Información del producto
Caspase-3 (4B8) Mouse mAb
Información adicional
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Applications
IHC
Concentration
1mg/mL
Recomended Dilution
IHC 1:100-200
Type Clonality
Monoclonal
Immunogen
Synthetic Peptide
Subcellular Location
Cytoplasm
Iso type
IgG1
Tissue Source
Mouse
Reactivity
Human, Rat, Mouse
Human Gen
836
Observed Band
17,32kDa
Other Name
APOPAIN antibody, CASP 3 antibody, CPP32 antibody, Cysterine protease CPP32 antibody
Background
Caspase-3 (CPP-32, Apoptain, Yama, SCA-1) is a critical executioner of apoptosis, as it is either partially or totally responsible for the proteolytic cleavage of many key proteins such as the nuclear enzyme poly(ADP-ribose) polymerase (PARP).