Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Applications
WB, IF
Concentration
1mg/mL
Recomended Dilution
WB 1:1,000-3,000 IF 1:100-200
Type Clonality
Monoclonal
Immunogen
Recombinant Protein
Subcellular Location
Cytoplasm, Mitochondrion
Iso type
IgG1
Tissue Source
Mouse
Reactivity
Human, Rat, Mouse
Human Gen
2271
Observed Band
50kDa
Other Name
Fumarase, fumarate hydratase, HLRCC, LRCC, MCL, MCUL1
Background
Fumarase (FH) is an enzyme that catalyzes the reversible hydration/dehydration of fumarate to malate. Fumarase comes in two forms: mitochondrial and cytosolic. The mitochondrial isoenzyme is involved in the Krebs Cycle (also known as the Tricarboxylic Aci