Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Applications
WB, IHC, IF
Concentration
1mg/mL
Recomended Dilution
100-200 IHC 1:200-500
WB 1:1,000 IF 1
Type Clonality
Monoclonal
Immunogen
Synthetic Peptide
Subcellular Location
Secreted and Cell membrane. Endoplasmic reticulum membrane
Iso type
IgG1
Tissue Source
Mouse
Reactivity
Human
Human Gen
1956
Observed Band
170kDa
Other Name
ER1
ERB-B1
Epidermal Growth Factor Receptor
ErbB-1
ErbB1
Erythroblastic Leukemia Viral(v-Erb-B)oncogene Homolog,Avian
HER1
MENA
Proto-oncogene c-ErbB-1
Receptor tyrosine-protein kinase erbB-1
Background
ErbB-1
HER1 in humans) is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF
The epidermal growth factor receptor (EGFR