Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Applications
WB, IHC, IF
Concentration
1mg/mL
Recomended Dilution
WB 1:1,000-2,000 IHC 1:200 IF 1:100-200
Type Clonality
Monoclonal
Immunogen
Synthetic Peptide
Subcellular Location
Mitochondrion outer membrane,Nucleus membrane,Endoplasmic reticulum membrane
Iso type
IgG1
Tissue Source
Mouse
Reactivity
Human, Rat, Mouse
Human Gen
596
Observed Band
26kDa
Other Name
B-Cell CLL/Lymphoma 2
B-Cell Leukemia/Lymphoma 2
Background
BCL2 is an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause o