Información del producto
Información adicional
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Applications
WB
Concentration
1mg/mL
Recomended Dilution
WB 1:1,000-2,000
Type Clonality
Polyclonal
Immunogen
Recombinant Protein
Subcellular Location
Cytoplasm, Nucleus
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human, Mouse, Rat
Human Gen
6416
Observed Band
44kDa
Other Name
JNK activating kinase 1, JNKK, JNKK1, MAP kinase kinase 4, MAP2K4, MAPK/ERK kinase 4, MAPKK 4, MAPKK4, MKK4, PRKMK4, SAPK/ERK kinase 1, SEK1, SERK1
Background
SAPK/Erk kinase (SEK1), also known as MEK4 or MKK4 or Jun kinase kinase (JNKK), activates the MAP kinase homologues SAPK and JNK in response to various cellular stresses and inflammatory cytokines . Activation of SEK1 occurs through MEKK phosphorylation o