Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Applications
WB, IHC
Concentration
1mg/mL
Recomended Dilution
WB 1:1,000-2,000 IHC 1:50-100
Type Clonality
Polyclonal
Immunogen
Synthetic Peptide
Subcellular Location
Cell membrane
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human, Rat, Mouse
Human Gen
7439
Observed Band
67kDa
Other Name
BEST antibody, Bestrophin-1 antibody, Best disease antibody, VMD 2 antibody
Background
Bestrophins were first found by genetic linkage of human-Bestrophin-1 (hBest1) to a juvenile form of macular degeneration called Best vitelliform macular dystrophy (BVMD). Forms calcium-sensitive chloride channels.