Información del producto
Información adicional
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Applications
IHC
Concentration
1mg/mL
Recomended Dilution
IHC 1:50-100
Type Clonality
Polyclonal
Immunogen
Recombinant Protein
Subcellular Location
Cell junction, Cytoplasm, Cytoplasmic vesicle, Cytoskeleton, Membrane, Mitochondrion, Mitochondrion inner membrane, Mitochondrion outer membrane, Nucleus, Synapse
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human, Rat, Mouse
Human Gen
598
Observed Band
30kDa
Other Name
B2CL1 antibody, Bcl 2 like 1antibody, Apoptosis regulator Bcl X antibody
Background
Bcl-xL prevents apoptosis through two different mechanisms: heterodimerization with an apoptotic protein inhibits its apoptotic effect and formation of mitochondrial outer membrane pores help maintain a normal membrane state under stressful conditions.