Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Applications
WB, IHC
Concentration
1mg/mL
Recomended Dilution
WB 1:1,000-2,000 IHC 1:50-100
Type Clonality
Polyclonal
Immunogen
Recombinant Protein
Subcellular Location
Cytoplasm
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human, Rat, Mouse
Human Gen
841
Observed Band
43,57kDa
Other Name
ALPS2B antibody, Apoptosis cysteine protease antibody, CAP4 antibody, CED3 antibody, MCH5 antibody
Background
Caspase-8 is a caspase protein, encoded by the CASP8 gene. It most likely acts upon caspase-3. Activated caspase-8 cleaves and activates downstream effector caspases such as caspase-1, -3, -6, and -7.