Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Applications
WB, IHC
Concentration
1mg/mL
Recomended Dilution
WB 1:2,000-5,000 IHC 1:200-500
Type Clonality
Polyclonal
Immunogen
Recombinant Protein
Subcellular Location
Cytoplasm,Nucleus
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human, Rat
Human Gen
4792
Observed Band
40kDa
Other Name
I kappa B alpha antibody, IkB-alpha antibody, IKBA antibody, MAD3 antibody, NFKB inhibitor antibody
Background
Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. IκBα phosphorylation and resulting Rel-dependent transcription are activated by a highly diverse group