Información del producto
Información adicional
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Applications
WB, IHC
Concentration
1mg/mL
Recomended Dilution
WB 1:1,000-2,000 IHC 1:500-1,000
Type Clonality
Polyclonal
Immunogen
Synthetic Peptide
Subcellular Location
Cytoplasm, Cytoplasm, Nucleus
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Rat, Mouse
Human Gen
7157
Observed Band
53kDa
Other Name
Cellular tumor antigen p53 antibody, Cys 51 stop antibody, Tp53 antibody, Tumor protein p53 antibody
Background
p53 plays a major role in the cellular response to DNA damage and other genomic aberrations. The activation of p53 can lead to either cell cycle arrest and DNA repair, or apoptosis. p53 is phosphorylated at multiple sites in vivo and by several different