Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Applications
WB
Concentration
1mg/mL
Recomended Dilution
WB 1:1,000-2,000
Type Clonality
Polyclonal
Immunogen
Recombinant Protein
Subcellular Location
Cytoplasm, Cytoplasmic vesicle, Endoplasmic reticulum, Endosome, Golgi apparatus, Membrane, Mitochondrion, Nucleus
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human, Rat, Mouse
Human Gen
8678
Observed Band
60kDa
Other Name
ATG6, Bcl-2 interacting protein beclin, BECN1, Coiled coil myosin like BCL2 interacting protein
Background
Autophagy is a catabolic process for the autophagosomic-lysosomal degradation of proteins activated in response to nutrient deprivation and in neurodegenerative conditions. One of the proteins critical to this process is Beclin-1.