Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Applications
WB, IHC
Concentration
1mg/mL
Recomended Dilution
WB 1:1,000-2,000 IHC 1:200-500
Type Clonality
Polyclonal
Immunogen
Synthetic Peptide
Subcellular Location
Cytoplasm,Cytoskeleton,Cell junction, Adherens junction
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human, Rat, Mouse
Human Gen
7414
Observed Band
130kDa
Other Name
CMD1W antibody, CMH15 antibody, metavinculin antibody, MVCL antibody, VINC antibody
Background
Vinculin is a membrane-cytoskeletal protein in focal adhesion plaques that is involved in linkage of integrin adhesion molecules to the actin cytoskeleton. Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is