Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Applications
WB, IHC, IF
Target
γ-H2AX
Research Area
Epigenetics
Form
liquid
Recomended Dilution
WB: 1:500-1:1000
Type Clonality
polyclonal
Immunogen
A synthetic phosphorylated peptide around S139 of human H2AX
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Histone H2AX (H2a/x)|Histone H2A.X|H2AX|H2AFX
Host
Rabbit
UniProt ID
P16104
Gene ID
3014
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse, Rat
Observed MW
17 kDa
Background
H2A.X becomes phosphorylated on serine 139 (to form gamma-H2AFX or H2AX139ph) in response to DNA double strand breaks (DSBs) generated by exogenous genotoxic agents and by stalled replication forks, which promotes DNA repair and maintains genomic stabilit