Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IHC, IF
Target
TAB3
Research Area
Immunology
Form
liquid
Recomended Dilution
WB: 1:500-1:1000
Type Clonality
polyclonal
Immunogen
TGF-beta-activated kinase 1 and MAP3K7-binding protein 3
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
TGF-beta-activated kinase 1 and MAP3K7-binding protein 3|Mitogen-activated protein kinase kinase kinase 7-interacting protein 3|NF-kappa-B-activating protein 1|TAK1-binding protein 3 (TAB-3)|TGF-beta-activated kinase 1-binding protein 3|TAB3|MAP3K7IP3
Host
Rabbit
UniProt ID
Q8N5C8
Gene ID
912
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse, Rat
Observed MW
75-100 kDa
Background
Adapter linking MAP3K7/TAK1 and TRAF6 or TRAF2. Mediator of MAP3K7 activation, respectively in the IL1 and TNF signaling pathways. Plays a role in activation of NF-kappa-B and AP1 transcription factor. Isoform 2 may be an oncogenic factor.