Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB
Target
PDK1
Research Area
Signal Transduction, Metabolism
Form
liquid
Recomended Dilution
WB: 1:500-1:2000
Type Clonality
polyclonal
Immunogen
pyruvate dehydrogenase kinase, isozyme 1
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial|Pyruvate dehydrogenase kinase isoform 1 (PDH kinase 1)|PDK1|PDHK1
Host
Rabbit
UniProt ID
Q15118
Gene ID
5163
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human
Observed MW
50 kDa
Background
Kinase that plays a key role in regulation of glucose and fatty acid metabolism and homeostasis via phosphorylation of the pyruvate dehydrogenase subunits PDHA1 and PDHA2. This inhibits pyruvate dehydrogenase activity, and thereby regulates metabolite flu