FT-FNab09143
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Size | 100µg |
Storage Conditions | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
Applications | ELISA, WB |
Target | UBA2 |
Research Area | Epigenetics, Metabolism |
Form | liquid |
Recomended Dilution | WB: 1:500-1:5000 |
Type Clonality | polyclonal |
Immunogen | ubiquitin-like modifier activating enzyme 2 |
Minimum Purity | ≥95% as determined by SDS-PAGE |
Synonyms | SUMO-activating enzyme subunit 2|Anthracycline-associated resistance ARX|Ubiquitin-like 1-activating enzyme E1B|Ubiquitin-like modifier-activating enzyme 2|UBA2|SAE2|UBLE1B |
Host | Rabbit |
UniProt ID | Q9UBT2 |
Gene ID | 10054 |
Purification | Immunogen affinity purified |
Iso type | IgG |
Reactivity | Human, Mouse |
Observed MW | 90 kDa |
Background | The heterodimer acts as a E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SA |