Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IP
Target
TDP2
Research Area
Signal Transduction
Form
liquid
Recomended Dilution
WB: 1:500-1:5000
Type Clonality
polyclonal
Immunogen
TRAF and TNF receptor associated protein
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Tyrosyl-DNA phosphodiesterase 2 (Tyr-DNA phosphodiesterase 2, hTDP2)|5'-tyrosyl-DNA phosphodiesterase (5'-Tyr-DNA phosphodiesterase)|ETS1-associated protein 2|ETS1-associated protein II (EAPII)|TRAF and TNF receptor-associated protein|Tyrosyl-RNA phosphod
Host
Rabbit
UniProt ID
O95551
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse, Rat
Observed MW
44 kDa
Background
TTRAP is a 5-prime tyrosyl-DNA phosphodiesterase that is required for efficient repair of topoisomerase II-induced DNA double-strand breaks. Thus it can remove lots of covalent adducts from DNA through hydrolysis of a 5'-phosphodiester bond, generating a