FT-FNab08832
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Size | 100µg |
Storage Conditions | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
Applications | ELISA, WB, IF, IHC |
Target | TNIP2 |
Research Area | Cardiovascular, Signal Transduction |
Form | liquid |
Recomended Dilution | WB: 1:500-1:2000 |
Type Clonality | polyclonal |
Immunogen | TNFAIP3 interacting protein 2 |
Minimum Purity | ≥95% as determined by SDS-PAGE |
Synonyms | TNFAIP3-interacting protein 2|A20-binding inhibitor of NF-kappa-B activation 2 (ABIN-2)|Fetal liver LKB1-interacting protein|TNIP2|ABIN2|FLIP1 |
Host | Rabbit |
UniProt ID | Q8NFZ5 |
Gene ID | 79155 |
Purification | Immunogen affinity purified |
Iso type | IgG |
Reactivity | Human, Mouse, Rat |
Observed MW | 50 kDa |
Background | Inhibits NF-kappa-B activation by blocking the interaction of RIPK1 with its downstream effector NEMO/IKBKG. Forms a ternary complex with NFKB1 and MAP3K8 but appears to function upstream of MAP3K8 in the TLR4 signaling pathway that regulates MAP3K8 activ |