Información del producto
SMURF1 antibody
Información adicional
Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IHC
Target
SMURF1
Research Area
Epigenetics, Metabolism, Developmental biology
Form
liquid
Recomended Dilution
WB: 1:500-1:2000
Type Clonality
polyclonal
Immunogen
SMAD specific E3 ubiquitin protein ligase 1
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
E3 ubiquitin-protein ligase SMURF1 (hSMURF1)|HECT-type E3 ubiquitin transferase SMURF1|SMAD ubiquitination regulatory factor 1|SMAD-specific E3 ubiquitin-protein ligase 1|SMURF1|KIAA1625
Host
Rabbit
UniProt ID
Q9HCE7
Gene ID
57154
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse, Rat
Observed MW
83-90 kDa
Background
E3 ubiquitin-protein ligase that acts as a negative regulator of BMP signaling pathway. Mediates ubiquitination and degradation of SMAD1 and SMAD5, 2 receptor-regulated SMADs specific for the BMP pathway. Promotes ubiquitination and subsequent proteasomal