Información del producto
SMAD4 antibody
Información adicional
Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IHC
Target
SMAD4
Research Area
Epigenetics, Signal Transduction, Metabolism, Cardiovascular, Immunology, Cancer, Developmental biology
Form
liquid
Recomended Dilution
WB: 1:500-1:2000
Type Clonality
polyclonal
Immunogen
SMAD family member 4
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Mothers against decapentaplegic homolog 4 (MAD homolog 4, Mothers against DPP homolog 4)|Deletion target in pancreatic carcinoma 4|SMAD family member 4 (SMAD 4, Smad4, hSMAD4)|SMAD4|DPC4|MADH4
Host
Rabbit
UniProt ID
Q13485
Gene ID
4089
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse, Rat
Observed MW
60 kDa
Background
In muscle physiology, plays a central role in the balance between atrophy and hypertrophy. When recruited by MSTN, promotes atrophy response via phosphorylated SMAD2/4. MSTN decrease causes SMAD4 release and subsequent recruitment by the BMP pathway to pr